Typhoid carriers and Vi agglutinins

Typhoid Fever and Typhoid Carriers

The Distribution of Typhoid Vi Agglutinins in Normal Sera with Special Reference to Their Diagnostic Value in Typhoid Fever

on the serological diagnosis using the conventional Widal test, the correct interpretation of the results of which is beset with many difficulties. The discovery by Felix and Pitt (1934) of a Vi antigen of B. typhosus, and its serumcounterpart Vi antibody in the sera of typhoid patients and carriers, opened up a new serological approach to the problem of diagnosis of typhoid infection. Bensted ...

Ampicillin Treatment of Typhoid Carriers.

THE change in the clinical course of typhoid fever due to treatment with chloramphenicol has been one of the more dramatic triumphs of the antibiotic age. A prolonged fever has been converted into a short sharp febrile illness, so that the patient suffering from the disease, instead of being dangerously ill for several weeks, may well be sitting up in bed after three or four days on chloramphen...

The Effect of Exercise on the Production of Typhoid Agglutinins *

The effects of exercise and of fatigue upon a variety of physiological responses in laboratory animals have been described by many authors, but few have extended the study to include the phenomenon of antibody responses in rabbits. An investigation of this question forms the basis of this note. That fatigue, or the attendant phenomena, decreases the susceptibility of the rat to subcutaneously i...

Detection of typhoid carriers by agglutination tests.

Use of the Vi agglutination test in the detection of chronic carriers of Salmonella typhi (S. typhosa) first was suggested by Felix et al. (1935). Since that time study of the test by many workers has resulted in the accumulation of a voluminous literature which has been reviewed by Klein (1943), Felix (1951), Landy and Lamb (1953), and Spaun (1957). Bhatnagar et al. (1938) recommended the use ...